The emergence of the plasmid-mediated colistin resistance gene mcr-1 is threatening the last-line role of colistin in human medicine. With mcr-1-positive Escherichia coli (E. coli) isolated from food animal being frequently reported in China. the prevalence of mcr-1 in food animal has attracted public attention. https://parisnaturalfoodes.shop/product-category/biosil/