BACKGROUND: MicroRNAs circulating in the blood. stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles. are currently being evaluated as biomarkers. The consequences of their differential association with lipids/vesicles for their stability and use as biomarkers are largely unexplored and are subject of the present study. https://foldlyers.shop/product-category/pal-and-coaxial/