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Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP

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Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs. Here. we report that RNF145. a previously uncharacterized ER membrane ubiquitin ligase. https://www.mainlandskateandsurfes.shop/product-category/mens-sandals/
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