Background: Oral squamous cell carcinoma (OSCC) and oropharyngeal squamous cell carcinoma (OPSCC) are very common in head and neck malignancy. Intratumour heterogeneity (ITH) may hamper their responses to treatment. Hence. novel tumour sampling methods that reflect ITH are required. https://www.gymnaziastore.com/product-category/plastic-moulds/